Intranasal Insulin Administration Does Not Affect LH Concentrations in Men with Diabetes
A quarter of men with obesity or type 2 diabetes have hypogonadotropic hypogonadism.Animal studies and in vitro data have shown that insulin action and insulin responsiveness in the brain are necessary for the maintenance of the functional integrity of the hypothalamo-hypophyseal-gonadal axis.We conducted a randomized, placebo-controlled trial to e